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the xenograft mouse model of melanoma is used
2008 Oct 10
20(2):188-90
26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28
InChiKey: YOHYSYJDKVYCJI-UHFFFAOYSA-N
Mpro inhibitor N3 hemihydrate 2684 the xenograft mouse model ofMpro inhibitor N3 hemihydrate is a potent inhibitor of SARS CoV 2 Mpro with an EC50 of 16. 77 M for SARS CoV 2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS CoV and MERS CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV 229E, FIPV, and MHV A59 with individual IC50 of 4. 0 M, 8. 8 M, and 2. 7 M, respectively. Product information Molecular Weight: 689. 80 Formula: C70H98N12O17
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